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1080 result(s) for 'immunology' within BMC Immunology

Page 21 of 22

  1. Fetuin-A/AHSH is a novel hepatokine that acts as a vascular calcification inhibitor and as an endogenous TLR-4 ligand. Fetuin-A may act as a positive or negative acute phase protein (APP) in disease conditions...

    Authors: Sardar Sindhu, Nadeem Akhter, Steve Shenouda, Ajit Wilson and Rasheed Ahmad
    Citation: BMC Immunology 2016 17:33
  2. C-reactive protein (CRP) exerts prothrombotic effects through dissociating from pentameric CRP (pCRP) into modified or monomeric CRP (mCRP). However, although the high prevalence of venous thromboembolism (VTE...

    Authors: Peng-cheng Xu, Shan Lin, Xiao-wei Yang, Dong-mei Gu, Tie-kun Yan, Li Wei and Bao-li Wang
    Citation: BMC Immunology 2015 16:10
  3. Systemic immune activation (inflammation) and immunosenescence develop in some people with advancing age. This process, known as “inflamm-aging,” is associated with physical frailty and sarcopenia. Meanwhile, ...

    Authors: Mark A. Wallet, Thomas W. Buford, Anna-Maria Joseph, Madhuri Sankuratri, Christiaan Leeuwenburgh, Marco Pahor, Todd Manini, John W. Sleasman and Maureen M. Goodenow
    Citation: BMC Immunology 2015 16:43
  4. Natural Killer (NK) cells are effector lymphocytes of the innate immune system and are subclassed into CD56BrightCD16Dim/− and CD56DimCD16+ NK cells. Intracellular calcium (Ca2+) is fundamental to regulate a numb...

    Authors: Cassandra Balinas, Helene Cabanas, Donald Staines and Sonya Marshall-Gradisnik
    Citation: BMC Immunology 2019 20:14
  5. Circulating bone marrow-derived monocytes can leave the blood, enter a tissue, and differentiate into M1 inflammatory, M2a remodeling/fibrotic, or M2c/Mreg resolving/immune-regulatory macrophages. Macrophages ...

    Authors: Darrell Pilling, Elkin Galvis-Carvajal, Tejas R. Karhadkar, Nehemiah Cox and Richard H. Gomer
    Citation: BMC Immunology 2017 18:30
  6. Immunologists often measure several correlated immunological markers, such as concentrations of different cytokines produced by different immune cells and/or measured under different conditions, to draw insigh...

    Authors: Bernd Genser, Joachim E. Fischer, Camila A. Figueiredo, Neuza Alcântara-Neves, Mauricio L. Barreto, Philip J. Cooper, Leila D. Amorim, Marcus D. Saemann, Thomas Weichhart and Laura C. Rodrigues
    Citation: BMC Immunology 2016 17:11
  7. Myeloid cells, especially mononuclear phagocytes, which include monocytes, macrophages and dendritic cells (DC), play vital roles in innate immunity, and in the initiation and maintenance of adaptive immunity....

    Authors: Hong Liu, Suryasarathi Dasgupta, Yu Fu, Brandi Bailey, Christian Roy, Eric Lightcap and Benjamin Faustin
    Citation: BMC Immunology 2019 20:42
  8. In genetically modified (GM) crops there is a risk that the inserted genes may introduce new allergens and/or adjuvants into the food and feed chain. The MON810 maize, expressing the insecticidal Cry1Ab toxin,...

    Authors: Monica Andreassen, Thomas Bøhn, Odd-Gunnar Wikmark, Johanna Bodin, Terje Traavik, Martinus Løvik and Unni Cecilie Nygaard
    Citation: BMC Immunology 2016 17:10
  9. Interleukin-15 is an immunostimulatory cytokine overexpressed in several autoimmune and inflammatory diseases such as Rheumatoid Arthritis, psoriasis and ulcerative colitis; thus, inhibition of IL-15-induced s...

    Authors: Yunier Rodríguez-Álvarez, Yanelys Morera-Díaz, Haydee Gerónimo-Pérez, Jorge Castro-Velazco, Rafael Martínez-Castillo, Pedro Puente-Pérez, Vladimir Besada-Pérez, Eugenio Hardy-Rando, Araceli Chico-Capote, Klaudia Martínez-Cordovez and Alicia Santos-Savio
    Citation: BMC Immunology 2016 17:30
  10. Cytokines, chemokines, adipocytokines, soluble cell receptors, and immune activation markers play an important role in immune responsiveness and can provide prognostic value since they reflect underlying condi...

    Authors: Najib Aziz, Roger Detels, Joshua J. Quint, David Gjertson, Timothy Ryner and Anthony W. Butch
    Citation: BMC Immunology 2019 20:33
  11. Potassium channel tetramerisation domain containing 9 (KCTD9), a member of KCTD family with a DNA-like pentapeptide repeat domain, was found to be increased particularly in NK cells of patients with HBV-induce...

    Authors: Xiaoping Zhang, Lin Zhu, Yaoyong Zhou, Aichao Shi, Hongwu Wang, Meifang Han, Xiaoyang Wan, Semvua Bukheti Kilonzo, Xiaoping Luo, Tao Chen and Qin Ning
    Citation: BMC Immunology 2018 19:20
  12. The saprophytic fungus Aspergillus fumigatus reproduces by generation of conidia, which are spread by airflow throughout nature. Since humans are inhaling certain amounts of spores every day, the (innate) immune ...

    Authors: Lothar Marischen, Anne Englert, Anna-Lena Schmitt, Hermann Einsele and Juergen Loeffler
    Citation: BMC Immunology 2018 19:39
  13. Both antibody secreting cells (ASCs) and memory B cells are essential for the maintenance of humoral immunity. To date, limit studies have focused on the two populations in Kawasaki disease (KD). To address th...

    Authors: Meng Xu, Yanfang Jiang, Jinghua Wang, Jinxiang Liu, Congcong Liu, Deying Liu and Sirui Yang
    Citation: BMC Immunology 2019 20:16
  14. Comprehensive understanding of cellular immune subsets involved in regulation of tumor progression is central to the development of cancer immunotherapies. Single cell immunophenotyping has historically been a...

    Authors: Elma Kadić, Raymond J. Moniz, Ying Huo, An Chi and Ilona Kariv
    Citation: BMC Immunology 2017 18:6
  15. Galectin-3 is known to be a lectin that plays an important role in inflammatory processes, acting as pro-inflammatory mediator in activation and migration of neutrophils and macrophages, as well as in the phag...

    Authors: Camila Brand, Thayse Pinheiro da Costa, Emerson Soares Bernardes, Camila Maria Longo Machado, Leonardo Rodrigues Andrade, Roger Chammas, Felipe Leite de Oliveira and Márcia Cury El-Cheikh
    Citation: BMC Immunology 2015 16:68
  16. Pepsin-trypsin resistant gliadin (PT-gliadin) promotes intestinal tissue inflammation and increases paracellular permeability of immunogenic gliadin peptides into the lamina propria. This leads to the complica...

    Authors: Naiyana Gujral, Ju Won Suh and Hoon H. Sunwoo
    Citation: BMC Immunology 2015 16:41
  17. To initiate mucosal immune responses, antigens in the intestinal lumen must be transported into gut-associated lymphoid tissue through M cells. Recently, it has been increasingly recognized that receptor activ...

    Authors: Jeong-In Kim, Tae-Eun Park, Sushila Maharjan, Hui-Shan Li, Ho-Bin Lee, In-Seon Kim, Dachuan Piao, Jun-Yeong Lee, Chong-Su Cho, Jin-Duck Bok, Zhong-Shan Hong, Sang-Kee Kang and Yun-Jaie Choi
    Citation: BMC Immunology 2015 16:71
  18. We have previously reported that interleukin-10 (IL-10) deficient dendritic cells (DCs) are potent antigen presenting cells that induced elevated protective immunity against Chlamydia. To further investigate the ...

    Authors: Khamia Ryans, Yusuf Omosun, Danielle N. McKeithen, Tankya Simoneaux, Camilla C. Mills, Nathan Bowen, Francis O. Eko, Carolyn M. Black, Joseph U. Igietseme and Qing He
    Citation: BMC Immunology 2017 18:27
  19. Serglycin proteoglycans are essential for maturation of secretory granules and for the correct granular storage of cationic proteases in hematopoietic cells, e.g. mast cells. However, little is known about the...

    Authors: Ananya Roy, Osama Sawesi, Ulrika Pettersson, Anders Dagälv, Lena Kjellén, Anna Lundén and Magnus Åbrink
    Citation: BMC Immunology 2016 17:15
  20. T cell activation induces ER stress and upregulates Inositol Requiring Enzyme 1 alpha (IRE1α), an activator of the unfolded protein response (UPR) pathway. Inhibition of IRE1α RNase activity in activated CD4+ spl...

    Authors: Cody Poe, Cheyanne Youngblood, Karissa Hodge and Kyeorda Kemp
    Citation: BMC Immunology 2019 20:3
  21. Multiple sclerosis (MS) is an autoimmune disease in which dysregulated immune cells attack myelin in the central nervous system (CNS), leading to irreversible neuronal degeneration. Our previous studies have d...

    Authors: Enyu Rao, Puja Singh, Yan Li, Yuwen Zhang, Young-In Chi, Jill Suttles and Bing Li
    Citation: BMC Immunology 2015 16:28
  22. IMGT®, the international ImMunoGeneTics information system® (http://​www.​imgt.​org), was created in 1989 in Montpellier, France (CNRS and Montpellier Uni...

    Authors: Véronique Giudicelli, Patrice Duroux, Sofia Kossida and Marie-Paule Lefranc
    Citation: BMC Immunology 2017 18:35
  23. Ulcerative colitis, an inflammatory bowel disease, is associated with the massive infiltration of neutrophils. Although the initial infiltration of neutrophils is beneficial for killing bacteria, it is presume...

    Authors: Sumika Tokieda, Marie Komori, Toshifumi Ishiguro, Yoichiro Iwakura, Kazuhiko Takahara and Kayo Inaba
    Citation: BMC Immunology 2015 16:64
  24. Melioidosis is endemic in Southeast Asia and Northern Australia and is caused by the Gram-negative, facultative intracellular pathogen Burkholderia pseudomallei. Diagnosis of melioidosis is often difficult becaus...

    Authors: Kei Amemiya, Jennifer L. Dankmeyer, Jeremy J. Bearss, Xiankun Zeng, Spencer W. Stonier, Carl Soffler, Christopher K. Cote, Susan L. Welkos, David P. Fetterer, Taylor B. Chance, Sylvia R. Trevino, Patricia L. Worsham and David M. Waag
    Citation: BMC Immunology 2020 21:5
  25. IFNγ-producing CD4+CD25+Foxp3+CD127- Treg represent the first line of Treg during an immune response. In the present study we determined whether IFNγ+ Treg in-vivo and in-vitro are Helios-positive representing...

    Authors: Volker Daniel, Karina Trojan, Martina Adamek and Gerhard Opelz
    Citation: BMC Immunology 2015 16:45
  26. Adoptive transfer of genetically engineered autologous T-cells is becoming a successful therapy for cancer. The avidity of the engineered T-cells is of crucial importance for therapy success. We have in the pa...

    Authors: Victoria Hillerdal, Vanessa F. Boura, Hanna Björkelund, Karl Andersson and Magnus Essand
    Citation: BMC Immunology 2016 17:23
  27. Homeostatic B Cell-Attracting chemokine 1 (BCA-1) otherwise known as CXCL13 is constitutively expressed in secondary lymphoid organs by follicular dendritic cells (FDC) and macrophages. It is the only known li...

    Authors: Ekaterina Klimatcheva, Tracy Pandina, Christine Reilly, Sebold Torno, Holm Bussler, Maria Scrivens, Alan Jonason, Crystal Mallow, Michael Doherty, Mark Paris, Ernest S Smith and Maurice Zauderer
    Citation: BMC Immunology 2015 16:6
  28. The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as HIV-1 and to investigate multiple aspects of human i...

    Authors: Raghubendra Singh Dagur, Amanda Branch-Woods, Saumi Mathews, Poonam S. Joshi, Rolen M. Quadros, Donald W. Harms, Yan Cheng, Shana M. Miles, Samuel J. Pirruccello, Channabasavaiah B. Gurumurthy, Santhi Gorantla and Larisa Y. Poluektova
    Citation: BMC Immunology 2019 20:2
  29. Down syndrome (DS) is the most common syndromic immunodeficiency with an increased risk of infection, mortality from sepsis, and autoinflammation. Innate immune function is altered in DS and therefore we exami...

    Authors: Dean Huggard, Fiona McGrane, Niamh Lagan, Edna Roche, Joanne Balfe, Timothy Ronan Leahy, Orla Franklin, Ana Moreno, Ashanty M. Melo, Derek G. Doherty and Eleanor J. Molloy
    Citation: BMC Immunology 2018 19:31
  30. Phenotype of chronic rhinosinusitis (CRS) may be an important determining factor of the efficacy of anti-inflammatory treatments. Although both glucocorticoids and macrolide antibiotics have been recommended f...

    Authors: Ming Zeng, Zhi-Yong Li, Jin Ma, Ping-Ping Cao, Heng Wang, Yong-Hua Cui and Zheng Liu
    Citation: BMC Immunology 2015 16:37
  31. Macrophages are tissue resident immune cells important for host defence and homeostasis. During diabetes, macrophages and other innate immune cells are known to have a pro-inflammatory phenotype, which is beli...

    Authors: Sofia Pavlou, Jaime Lindsay, Rebecca Ingram, Heping Xu and Mei Chen
    Citation: BMC Immunology 2018 19:24
  32. Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease caused by the selective destruction of pancreatic β cells, followed by hyperglycemia, oxidative stress and the subsequent extensive impairment of ...

    Authors: Ahmad A. Al Ghamdi, Gamal Badr, Wael N. Hozzein, Ahmed Allam, Noori S. Al-Waili, Mohammed A. Al-Wadaan and Olivier Garraud
    Citation: BMC Immunology 2015 16:54
  33. We previously reported that JAK–STAT-pathway mediated regulation of IFN-regulatory factor genes could play an important role in SLE pathogenesis. Here, we evaluated the efficacy of the JAK inhibitor tofacitini...

    Authors: Keigo Ikeda, Kunihiro Hayakawa, Maki Fujishiro, Mikiko Kawasaki, Takuya Hirai, Hiroshi Tsushima, Tomoko Miyashita, Satoshi Suzuki, Shinji Morimoto, Naoto Tamura, Kenji Takamori, Hideoki Ogawa and Iwao Sekigawa
    Citation: BMC Immunology 2017 18:41
  34. Despite effective antiretroviral therapy (ART), HIV-infected patients exhibit systemic inflammation, early onset of age-related diseases, and features of immunosenescence. The role of inflammation in the devel...

    Authors: Juliette Tavenier, Anne Langkilde, Thomas Huneck Haupt, Jens Henrik Henriksen, Frank Krieger Jensen, Janne Petersen and Ove Andersen
    Citation: BMC Immunology 2015 16:72
  35. Cancer therapeutic vaccine induced cytotoxic T cell (CTL) responses are pivotal for the killing of tumour cells. Blocking interleukin 10 (IL-10) signalling at the time of immunization increases vaccine induced...

    Authors: Guoying Ni, Zaowen Liao, Shu Chen, Tianfang Wang, Jianwei Yuan, Xuan Pan, Kate Mounsey, Shelley Cavezza, Xiaosong Liu and Ming Q. Wei
    Citation: BMC Immunology 2017 18:40
  36. Autoimmune diseases result from aberrant immune attacks by the body itself. It is mysterious how autoantigens, a large cohort of seemingly unconnected molecules expressed in different parts of the body, can in...

    Authors: Wei Zhang, Jung-hyun Rho, Michael H. Roehrl and Julia Y. Wang
    Citation: BMC Immunology 2019 20:21
  37. Besides their prominent role in the elimination of infected or malignantly transformed cells, natural killer (NK) cells serve as modulators of adaptive immune responses. Enhancing bidirectional crosstalk betwe...

    Authors: Tammy Oth, Thomas H. P. M. Habets, Wilfred T. V. Germeraad, Marijke I. Zonneveld, Gerard M. J. Bos and Joris Vanderlocht
    Citation: BMC Immunology 2018 19:8
  38. Vaccination generating a robust memory population of CD8+ T cells may provide protection against cancer. However, immune therapies for cancer are influenced by the local tumour immune microenvironment. An infiltr...

    Authors: Andrew J. Highton, Adam Girardin, Georgia M. Bell, Sarah M. Hook and Roslyn A. Kemp
    Citation: BMC Immunology 2016 17:39
  39. The chronic course of pulmonary sarcoidosis can lead to lung dysfunction due to fibrosis, in which the signalling pathways TGF-β/Smad and VEGF-A may play a key role.

    Authors: Wojciech J. Piotrowski, Justyna Kiszałkiewicz, Paweł Górski, Adam Antczak, Witold Górski, Dorota Pastuszak-Lewandoska, Monika Migdalska-Sęk, Daria Domańska-Senderowska, Ewa Nawrot, Karolina H. Czarnecka, Zofia Kurmanowska and Ewa Brzeziańska-Lasota
    Citation: BMC Immunology 2015 16:58
  40. The purpose of this study was to characterize specific cytotoxic T-cell (CTL) responses in men who have sex with men (MSM) subjects infected with the human immunodeficiency virus type 1 (HIV-1) CRF01_AE subtyp...

    Authors: Fanming Jiang, Xiaoxu Han, Hui Zhang, Bin Zhao, Minghui An, Junjie Xu, Zhenxing Chu, Tao Dong and Hong Shang
    Citation: BMC Immunology 2016 17:28
  41. Immunoglobulin A nephropathy (IgAN), membranous nephropathy (MN) and minimal-change disease (MCD) are three common types of glomerulonephritis in China. Pathological diagnosis based on renal biopsy is the crit...

    Authors: Jin Dong, Tianhao Peng, Jing Gao, Xingwang Jia, Guangtao Yan and Yong Wang
    Citation: BMC Immunology 2018 19:18
  42. Hyperactive secretion and pathogenic effects of interleukin (IL)-17 and IgA have been detected in different arthropathies. Recent evidence has revealed that TH17 cytokines regulate mucosal IgA secretion. However,...

    Authors: Ricardo Javier Eliçabe, Juan Eduardo Silva, Mabel Noemí Dave, María Gabriela Lacoste, Héctor Tamashiro, Rodrigo Blas, Alicia Munarriz, Gabriel Adrián Rabinovich and María Silvia Di Genaro
    Citation: BMC Immunology 2017 18:8
  43. The need for rapid and accurate comparison of panels of adjuvanted vaccine formulations and subsequent rational down selection, presents several challenges for modern vaccine development. Here we describe a me...

    Authors: Sumera Y. Younis, Christophe Barnier-Quer, Simon Heuking, Vinod Sommandas, Livia Brunner, Nicole vd.Werff, Patrice Dubois, Martin Friede, Clemens Kocken, Nicolas Collin and Ed Remarque
    Citation: BMC Immunology 2018 19:6
  44. The aim of the current study was to investigate the long non-coding RNA (lncRNA) expression profiles in psoriatic arthritis (PSA) patients by RNA sequencing, and to further explore potential biomarkers that we...

    Authors: Tao Yue, Mei Ji, Huanru Qu, Mengru Guo, Fengmin Bai, Zhanming Zhang, Weifeng Wang, Xuming Gong and Zhenghua Zhang
    Citation: BMC Immunology 2019 20:28
  45. All-trans retinoid acid (ATRA) has been proven to skew Regulatory T cell-T helper 17 cell (Treg-Th17) balance toward Treg in vitro, favoring graft acceptance. However, its in vivo effect after solid organ transpl...

    Authors: Xin Wang, Wentao Wang, Jianjiang Xu, Suqian Wu and Qihua Le
    Citation: BMC Immunology 2015 16:17

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