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1171 result(s) for 'immunology' within BMC Immunology

Page 4 of 24

  1. Allergic sensitisation has been ascribed to a dysregulated relationship between allergen-specific Th1, Th2 and regulatory T cells. We sought to utilise our short-term CD154 detection method to further analyse ...

    Authors: Karen A Smith, Nicola J Gray, Femi Saleh, Elizabeth Cheek, Anthony J Frew, Florian Kern and Michael D Tarzi
    Citation: BMC Immunology 2013 14:49
    Content type: Research article Published on:

  3. Highly purified nuclear protein is required when using an electrophoretic mobility shift assay (EMSA) to study transcription factors, e.g. nuclear factor-κB (NF-κB), a major transcription factor that regulates bo...

    Authors: Yuqian Luo, Takeshi Hara, Yuko Ishido, Aya Yoshihara, Kenzaburo Oda, Masahiko Makino, Norihisa Ishii, Naoki Hiroi and Koichi Suzuki
    Citation: BMC Immunology 2014 15:586
    Content type: Methodology article Published on:

  5. Outcome prediction for patients with sepsis may be conductive to early aggressive interventions. Numerous biomarkers and multiple scoring systems have been utilized in predicting outcomes, however, these tools...

    Authors: Lin Zhang, Cui-hua Yu, Kuan-peng Guo, Cai-zhi Huang and Li-ya Mo
    Citation: BMC Immunology 2020 21:40
    Content type: Research article Published on:

  6. S100A9 has been shown to be important for the function of so called Myeloid Derived Suppressor Cells (MDSC). Cells with a similar phenotype are also involved in pro-inflammatory processes, and we therefore wan...

    Authors: Eva Källberg, Martin Stenström, David Liberg, Fredrik Ivars and Tomas Leanderson
    Citation: BMC Immunology 2012 13:69
    Content type: Research article Published on:

  7. Successful inhibition of alloimmune activation in organ transplantation remains one of the key events in achieving a long-term graft survival. Since T lymphocytes are largely responsible for alloimmune activat...

    Authors: Ashwani K Khanna and Mandeep R Mehra
    Citation: BMC Immunology 2006 7:26
    Content type: Research article Published on:

  8. Signal transducer and activator of transcription 1 (STAT1) is a critical component of interferon (IFN)-alpha/beta and IFN-gamma signaling. Although seven isoforms of STAT proteins have been reported from mamma...

    Authors: Eun-Mi Park, Jung-Ha Kang, Jung Soo Seo, GunDo Kim, Jongkyeong Chung and Tae-Jin Choi
    Citation: BMC Immunology 2008 9:31
    Content type: Research article Published on:

  9. Previous reports indicate that ethanol, in a binge drinking model in mice, inhibits the production of pro-inflammatory cytokines in vivo. However, the inhibition of signaling through TLR4 has not been investig...

    Authors: Stephen B Pruett and Ruping Fan
    Citation: BMC Immunology 2009 10:49
    Content type: Research article Published on:

  10. Excessive inflammatory response is the primary cause of early death in patients with endotoxemia. Interleukin 22 (IL-22) has been shown to play critical roles in the modulation of infectious diseases, but its ...

    Authors: Chang Yu, Qihua Ling, Junzhe Jiao, Juhong Liu, Zhihua Huang, Fang Wang, Xuehua Sun and Xiaoni Kong
    Citation: BMC Immunology 2022 23:45
    Content type: Research Published on:

  12. Pro-inflammatory cytokines can affect intracellular lipid metabolism. A variety of effects have been described for different cell types; hepatocyte lipid turnover pathways are inhibited during inflammation, wh...

    Authors: Jenny Persson, Jan Nilsson and Marie W Lindholm
    Citation: BMC Immunology 2008 9:70
    Content type: Research article Published on:

  13. Sequence analysis of immunoglobulin heavy chain (IGH) gene rearrangements and frequency analysis is a powerful tool for studying the immune repertoire, immune responses and immune dysregulation in health and d...

    Authors: Michael J Moorhouse, David van Zessen, Hanna IJspeert, Saskia Hiltemann, Sebastian Horsman, Peter J van der Spek, Mirjam van der Burg and Andrew P Stubbs
    Citation: BMC Immunology 2014 15:59
    Content type: Software Published on:

  14. Burkholderia pseudomallei (Bp) is a category B biothreat organism that causes a potentially fatal disease in humans and animals, namely melioidosis. Burkholderia thailandensis (Bt) is another naturally occurring ...

    Authors: Jaruek Charoensap, Pongsak Utaisincharoen, Anneke Engering and Stitaya Sirisinha
    Citation: BMC Immunology 2009 10:20
    Content type: Research article Published on:

  15. Dendritic cells (DCs) initiate immune responses through their direct interaction with effector cells. However, the mechanism by which DC activity is regulated is not well defined. Previous studies have shown t...

    Authors: Xiong B Wang, Zhong Z Fan, Doina Anton, Annika V Vollenhoven, Zhen H Ni, Xiao F Chen and Ann K Lefvert
    Citation: BMC Immunology 2011 12:21
    Content type: Research article Published on:

  16. The proteoliposome derived from Vibrio cholerae O1 (PLc) is a nanoscaled structure obtained by a detergent extraction process. Intranasal (i.n) administration of PLc was immunogenic at mucosal and systemic level ...

    Authors: Reinaldo Acevedo, Adriana Callicó, Yisabel Aranguren, Caridad Zayas, Yolanda Valdés, Oliver Pérez, Luis García, Valerie A Ferro and José Luis Pérez
    Citation: BMC Immunology 2013 14(Suppl 1):S10
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  18. The necessity of the tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine in adolescence and adults has been emphasized since the resurgence of small-scale pertussis in Korea and worldwide due to...

    Authors: Kyu Ri Kang, Dong Ho Huh, Ji Ahn Kim and Jin Han Kang
    Citation: BMC Immunology 2021 22:68
    Content type: Research article Published on:

  19. Lung cancer with the highest incidence and mortality in the world. Immune checkpoint inhibitors (ICIs), can bring long-term survival benefits to patients, but also can bring immune-related adverse events (irAE...

    Authors: Kailian Hou, Weipeng Ye, Qunfeng Huang, Weiyi Li, Zhiqiong Tan, Na tao, Dongheng yang, Haoxin Lin, Zihao Deng, Yuanyuan Xia and Guifang Yu
    Citation: BMC Immunology 2024 25:3
    Content type: Research Published on:

  20. There is increasing evidence to suggest an immunomodulation function both within the intestines and systemically upon consuming probiotic species. We recently isolated a novel LAB, Lactobacillus casei Zhang (LcZh...

    Authors: Tuo Ya, Qijin Zhang, Fuliang Chu, Justin Merritt, Menhe Bilige, Tiansong Sun, Ruiting Du and Heping Zhang
    Citation: BMC Immunology 2008 9:68
    Content type: Research article Published on:

  21. Chemokines immobilized on endothelial cells play a central role in the induced firm adhesion and transendothelial migration of leukocytes. Activation of platelets at sites of vascular injury is considered to s...

    Authors: Christian Weingart, Peter J Nelson, Bernhard K Krämer and Matthias Mack
    Citation: BMC Immunology 2008 9:72
    Content type: Research article Published on:

  22. Single-cell assays of immune function are increasingly used to monitor T cell responses in immunotherapy clinical trials. Standardization and validation of such assays are therefore important to interpretation...

    Authors: Holden T Maecker, Jeffrey Hassler, Janice K Payne, Amanda Summers, Karrie Comatas, Manar Ghanayem, Michael A Morse, Timothy M Clay, Herbert K Lyerly, Sonny Bhatia, Smita A Ghanekar, Vernon C Maino, Corazon delaRosa and Mary L Disis
    Citation: BMC Immunology 2008 9:9
    Content type: Methodology article Published on:

  23. Autoantibodies against glutamate decarboxylase-65 (GAD65Abs) are thought to be a major immunological tool involved in pathogenic autoimmunity development in various diseases. GAD65Abs are a sensitive and specific...

    Authors: Mohd Wajid Ali Khan, Kamalpreet Banga, Subhash N Mashal and Wahid Ali Khan
    Citation: BMC Immunology 2011 12:19
    Content type: Research article Published on:

  24. The assortment of cattle immunoglobulin and surrogate light chain genes has been extracted from the version 3.1 of Bos taurus genome sequence as a part of an international effort to sequence and annotate the bovi...

    Authors: Anna Ekman, Mikael Niku, Jenni Liljavirta and Antti Iivanainen
    Citation: BMC Immunology 2009 10:22
    Content type: Research article Published on:

  25. No reliable biological marker for the diagnosis of asthma in younger children is currently available. In this study, we analyzed the differences in basophil activation test (BAT) results among children with re...

    Authors: Jingyang Li, Jinhong Wu, Haipei Liu, Li Hua, Quanhua Liu, Dingzhu Fang, Yi Chen, Ruoxu Ji, Jianhua Zhang and Wenwei Zhong
    Citation: BMC Immunology 2021 22:4
    Content type: Research Published on:

  26. Proteoliposomes purified from the Outer Membrane of Neisseria meningitidis B, have been successfully used as core for adjuvants and vaccine formulations. We have tried to increase their structural definition and ...

    Authors: Beatriz Tamargo, Yanet Márquez, Wendy Ramírez, Bárbara Cedré, Manuel Fresno and Gustavo Sierra
    Citation: BMC Immunology 2013 14(Suppl 1):S12
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 14 Supplement 1

  29. Inflammatory bowel disease constitutes a heterogeneous group of conditions, whose aetiology is only partly understood. The prevailing hypothesis on its pathogenesis is that IBD is the result of an inadequate i...

    Authors: Natalie Frede, Erik-Oliver Glocker, Jennifer Wanders, Karin R Engelhardt, Wolfgang Kreisel, Frank M Ruemmele and Bodo Grimbacher
    Citation: BMC Immunology 2014 15:10
    Content type: Research article Published on:

  30. Selenium, a micronutrient whose deficiency in diet causes immune dysfunction and inflammatory disorders, is thought to exert its physiological effects mostly in the form of selenium-containing proteins (seleno...

    Authors: Bradley A Carlson, Min-Hyuk Yoo, Yasuyo Sano, Aniruddha Sengupta, Jin Young Kim, Robert Irons, Vadim N Gladyshev, Dolph L Hatfield and Jin Mo Park
    Citation: BMC Immunology 2009 10:57
    Content type: Research article Published on:

  31. CC-family chemokine receptor 2 (CCR2) is implicated in the trafficking of blood-borne monocytes to sites of inflammation and is implicated in the pathogenesis of several inflammatory diseases such as rheumatoi...

    Authors: Deshun Lu, Xiu-juan Yuan, Robert J Evans Jr, Amy T Pappas, He Wang, Eric W Su, Chafiq Hamdouchi and Chandrasekar Venkataraman
    Citation: BMC Immunology 2005 6:15
    Content type: Research article Published on:

  32. Mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus and its derivative, everolimus, are potent immunosuppressive and antiproliferative drugs. Inflammatory diseases are characterized by immunolog...

    Authors: Hugo You-Hsien Lin, Kai-Ting Chang, Chi-Chih Hung, Chang-Hung Kuo, Shang-Jyh Hwang, Hung-Chun Chen, Chih-Hsing Hung and Sheng-Fung Lin
    Citation: BMC Immunology 2014 15:37
    Content type: Research article Published on:

  33. The challenge of gene expression studies is to reliably quantify levels of transcripts, but this is hindered by a number of factors including sample availability, handling and storage. The PAXgene™ Blood RNA S...

    Authors: Enitan D Carrol, Fiona Salway, Stuart D Pepper, Emma Saunders, Limangeni A Mankhambo, William E Ollier, C Anthony Hart and Phillip Day
    Citation: BMC Immunology 2007 8:20
    Content type: Research article Published on:

  34. Extensive allelic matching in the human leukocyte antigen (HLA) genes is regarded as a prerequisite for good clinical success of allogeneic haematopoietic stem cell transplantation (HSCT). Also other genetic f...

    Authors: Jyrki Sivula, Hannu Turpeinen, Liisa Volin and Jukka Partanen
    Citation: BMC Immunology 2009 10:24
    Content type: Research article Published on:

  35. Foxp3 protein plays a critical role in mediating the inflammatory response and can inhibit the proinflammatory IL-23/IL-17 pathway. However, the molecular interplay of Foxp3 and the IL-23/IL-17 pathway in pati...

    Authors: Qinghong Wang, Yanhua Zheng, Zemin Huang, Yi Tian, Jijun Zhou, Qing Mao, Yuzhang Wu and Bing Ni
    Citation: BMC Immunology 2011 12:25
    Content type: Research article Published on:

  37. Lymphoid tissues constitute basic structures where specific immune responses take place. This leads to the development of germinal centres (GCs), migration of cells and the generation of memory cells. Here, we...

    Authors: Berta Vidal-Rubio, Marta Sanchez-Carril, Josefina Oliver-Morales, África González-Femandez and Francisco Gambón-Deza
    Citation: BMC Immunology 2001 2:2
    Content type: Research article Published on:

  39. Nonsteroidal anti-inflammatory drugs (NSAID) represent a one of the most widely used anti-inflammatory substances. Their anti-inflammatory effects are mainly based on inhibition of cyclooxygenase. The potentia...

    Authors: Saulius Paskauskas, Audrius Parseliunas, Vachtang Kerkadze, Rainer Nobiling, Jan Schmidt and Eduard Ryschich
    Citation: BMC Immunology 2011 12:64
    Content type: Research article Published on:

  40. Health care workers (HCWs) are at risk for occupationally acquired Mycobacterium tuberculosis infection and tuberculosis (TB) disease due to repeated exposure to workplace tubercle bacilli. To determine whether c...

    Authors: Cui-lin Shi, Jian-ping Zhang, Ping Xu, Jin Li, Jie Shen, Mei-ying Wu, Zhi-jian Ye, Xin Yu, Hua-feng Song, Hui Chen, Jun-chi Xu, Yu Pang and Jian-an Huang
    Citation: BMC Immunology 2021 22:39
    Content type: Research Published on:

  41. The chemokine CXCL1, known as growth-related oncogene α (GRO-α), is a potent chemoattractant and regulator of neutrophils. The purpose of our study was to evaluate the regulatory response of CXCL1 in the serum...

    Authors: Yanli Zeng, Qiaoduan Lin, Liang Yu, Xuelian Wang, Yiqiang Lin, Yan Zhang, Shuidi Yan, Xinxin Lu, Yijing Li, Weibin Li and Yun Xiao
    Citation: BMC Immunology 2021 22:82
    Content type: Research Published on:

  42. The obligate intracellular bacterial pathogen Coxiella burnetii causes the zoonosis Q fever. The intracellular niche of C. burnetii has led to the assumption that cell-mediated immunity is the most important immu...

    Authors: Jeffrey G Shannon, Diane C Cockrell, Kazue Takahashi, Gregory L Stahl and Robert A Heinzen
    Citation: BMC Immunology 2009 10:26
    Content type: Research article Published on:

  43. We previously showed that co-immunization with a protein antigen and a DNA vaccine coding for the same antigen induces CD40low IL-10high tolerogenic DCs, which in turn stimulates the expansion of antigen-specific...

    Authors: Shuang Geng, Yang Yu, Youmin Kang, George Pavlakis, Huali Jin, Jinyao Li, Yanxin Hu, Weibin Hu, Shuang Wang and Bin Wang
    Citation: BMC Immunology 2011 12:27
    Content type: Research article Published on:

  44. Ganoderma lucidum-derived polysaccharide (PS-G) can rapidly and effectively promote the activation and maturation of immature dendritic cells (DCs), suggesting that PS-G possesses the capacity to regulate immune ...

    Authors: Rong-Hwa Jan, Teng-Yi Lin, Ya-Chun Hsu, Shiuh-Sheng Lee, Shih-Yen Lo, Mingi Chang, Li-Kuang Chen and Yu-Li Lin
    Citation: BMC Immunology 2011 12:31
    Content type: Research article Published on:

  45. Inflammatory arthritis including rheumatoid arthritis (RA) and spondyloarthritis (SpA) is characterized by inflammation and destruction of the joints. Approximately one third of patients do not respond to firs...

    Authors: A. L. Hansen, L. S. J. Rahbek, A. S. Sørensen, M. P. Hundahl, S. Lomholt, C. K. Holm and Tue W. Kragstrup
    Citation: BMC Immunology 2021 22:77
    Content type: Research Published on:

  46. Measles outbreaks have threatened the global elimination and eradication of measles in recent years. Measles virus (MeV)-specific antibodies are successful in clearing MeV infection. Follicular helper T (Tfh) ...

    Authors: Weiyun Shen, Hongzhou Ye, Xilin Zhang, Lixia Huo, Jingli Shen, Li Zhu, Xiang Wang and Dawei Cui
    Citation: BMC Immunology 2020 21:49
    Content type: Research article Published on:

  47. Alopecia areata (AA) is a common inflammatory disorder targeting the hair follicles leading to non-scaring hair loss. The pathogenesis of AA is still unclear, despite the accumulating evidence of the immune-me...

    Authors: Abdel-Khalek Younes, Refaat Hammad, Mona Othman and Ali Sobhy
    Citation: BMC Immunology 2022 23:13
    Content type: Research Published on:

  48. Dipeptidyl peptidase IV, a multifunctional serine protease, is implicated in regulation of malignant transformation, promotion and further progression of cancer, exerting tumor-suppressing or even completely o...

    Authors: Ivana Z Matić, Marija Đorđić, Nađa Grozdanić, Ana Damjanović, Branka Kolundžija, Aleksandra Erić-Nikolić, Radan Džodić, Miomir Šašić, Srđan Nikolić, Danijela Dobrosavljević, Sanvila Rašković, Slađana Andrejević, Dušica Gavrilović, Oscar J Cordero and Zorica D Juranić
    Citation: BMC Immunology 2012 13:48
    Content type: Research article Published on:

  49. Brucellar spondylitis (BS) is one of the most serious complications of brucellosis. CXCR3 is closely related to the severity of disease infection. This research aimed to study the degree of BS inflammatory dam...

    Authors: Xin Hu, Xiaoqian Shang, Liang Wang, Jiahui Fan, Yue Wang, Jie Lv, Shaxika Nazierhan, Hao Wang, Jing Wang and Xiumin Ma
    Citation: BMC Immunology 2020 21:59
    Content type: Research article Published on:

  50. Immunity to food antigens (gliadin, cow's milk proteins) is in the centre of the attention of modern medicine focused on the prevention of diseases, prevention which is based on the use of appropriate restrict...

    Authors: Aleksandra Konic-Ristic, Dejan Dodig, Radmilo Krstic, Svetislav Jelic, Ivan Stankovic, Aleksandra Ninkovic, Jelena Radic, Irina Besu, Branka Bonaci-Nikolic, Njegica Jojic, Milica Djordjevic, Dragan Popovic and Zorica Juranic
    Citation: BMC Immunology 2009 10:32
    Content type: Research article Published on:

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